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==== Biologie für Fortgeschrittene ==== | |||
[http://www.youtube.com/watch?v=AkMdZPsM4No&feature=related Legostein 13] Legoanimation. | |||
--[[User:Sebastian|sebastian]] 11:59, 22 September 2010 (CEST) | |||
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==== cells.de - Der Onlinedienst zur Zellbiologie mit Videos und interaktiven Medien ==== | |||
http://www.cells.de/cellsger/index.jsp | |||
<br> | |||
--[[User:Sebastian|sebastian]] 21:31, 2 September 2010 (CEST) | |||
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==== Interesting Reading: '''Das Buch des Lebens''' ==== | |||
"Das Buch des Lebens: wer schrieb den genetischen Code?" von Lily E. Kay. | |||
ISBN 3-518-29346-X | |||
Recommended by [[User:Felixsattler|Felix Sattler]]<br> | |||
--[[User:Sebastian|sebastian]] 19:44, 2 September 2010 (CEST) | |||
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==== Bio:Fiction Filmfestival about Synthetic Biology - !!DEADLINE EXTENDED!! ==== | |||
The new deadline will be ''December 1st 2010!'' [http://www.bio-fiction.com/Home.html Hurry up!] | |||
--[[User:Sebastian|sebastian]] 15:28, 22 July 2010 (UTC) | |||
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====iGEM: Preliminary Project Descriptions Due==== | |||
As the iGEM [http://2010.igem.org/Calendar_of_Events calender of events] shows the [http://2010.igem.org/Preliminary_Project_Description preliminary project description] is due on 16. of july. | |||
Please do not forget to take care of that. | |||
--[[User:Sebastian|sebastian]] 17:54, 7 July 2010 (UTC) | |||
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===="Wir wissen nichts"==== | |||
[http://www.spiegel.de/spiegel/0,1518,703085,00.html Spiegel Interview] with Craig Venter | |||
--[[User:Sebastian|sebastian]] 10:43, 5 July 2010 (UTC) | |||
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==== Marke.6 layout==== | |||
I have uploaded the newest version layout of Marke.6 application in dropbox. <br/> | |||
But Mila said she didn't see it. So I upload it to wiki now. [http://web.uni-weimar.de/medien/wiki/File:Marke.6_layout4.pdf here is it!]<br/> | |||
--[[User:Sharklu|Sharklu]] 21:37, 4 July 2010 (UTC) Lu Jiayuan | |||
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==== Artifacts from the future (Wired)==== | |||
In each issue of Wired magazine, at the end of the book, there’s a page called “artifact from the future” that consists in a heavily photoshopped photo of an object supposedly common in the future. These visual elements depicts designers, researchers, pundits’ prognostications about how the world “will look like in 10, 20 or 100 years“. Yes, it’s “will” not “may”, as shown in this article. See some examples systematically listed by sceptycal futurist [http://futuryst.blogspot.com/2008/03/compleat-wired-future-artifacts-gallery.html Stuart Candy] | |||
--[[User:Bernd|Bernd]] 19:45, 2 July 2010 (UTC) | |||
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==== Knockout Moss==== | |||
There is also some more information about the moss on Prof. Dr. Ralf Reski's homepage of University Freiburg: | |||
http://www.plant-biotech.net/ | |||
Yeah and the best about this moss is....you can order it!!! | |||
At the university of freiburg international moss stock center: | |||
http://www.moss-stock-center.org/ | |||
And that only for 50€ per mutant knock-out plant and only 5€ for the ecotype physcomitrella patens moss! | |||
ah yeah plus shipping! | |||
--[[User:Wawa|Wawa]] 13:52, 30 June 2010 (UTC) | |||
In co-operation with the chemical company BASF Ralf Reski and coworkers established a collection of knockout mosses that is used for gene identification | |||
last passage here: | |||
[[wikipedia:de:Knockout Moss]] | |||
--[[User:Bernd|Bernd]] 19:45, 2 July 2010 (UTC) | |||
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==== Epigenetics ==== | |||
[http://video.google.com/videoplay?docid=1128045835761675934#/The Ghost in your genes] | |||
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==== DIY Bio: Open Gel Box 2.0 ==== | |||
A DIY Gel electrophoresis box | |||
from [http://www.pearlbiotech.com/ Pearl Biotech] | |||
see also [http://openwetware.org/wiki/DIYbio:Notebook/Open_Gel_Box_2.0 here]. | |||
--[[User:Sebastian|sebastian]] 15:16, 23 June 2010 (UTC) | |||
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==== Cellularity==== | |||
<videoflash type=vimeo>10274649|600|340</videoflash> | |||
The central idea behind this scenario is that we might one day understand life, not as a hard-edged category, but as a graduated scale between nonliving and living things. Each developmental stage in chemical cell biology is slightly more alive than the stage before. To formalize this idea, I designed a speculative definition of life named the “Cellularity Scale” which shows how five different living properties accumulate at each subsequent stage. Of course, this is a purely speculative definition of life, consistent with the scenario I have designed. If the Chell project or any of the several other bottom-up attempts at abiogenesis are successful, they will quite possibly offer an entirely different picture. | |||
[http://www.james-king.net/projects/cellularity James King] | |||
James' [http://seedmagazine.com/content/article/slippery_cellularities/ article] on Seedmagazine.com | |||
--[[User:Bernd|Bernd]] 15:35, 22 June 2010 (UTC) | |||
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==== AI Game==== | |||
Just found on the c't magazine: [http://antme.net/description.html antme],a software simulating ants which behave according to an artificial intelligence. The AI needs to be coded beforehand. The project is aimed to C# beginners to teach programming. I see some parallels to our bacteria-game: we "code" DNA, it takes place in a closed environment etc. | |||
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==== Game and iGEM Project 2008 ==== | |||
Just a first, (finally not so) brief comment on the idea of making a kind of computer game, but with genetically modified bacteria. As some of you might already know, the iGEM project of our team in 2008 was about creating an artificial preditor-prey system by genetically modifying bacteria. We wanted therefore to create bacteria that would:<br/> | |||
a) swim towards a target bacteria <br/> | |||
b) kill that target bacteria when it would reach it<br/> | |||
The second part (killing) worked really good, but the first part (swimming towards a certain target) didn't work out so good. | |||
But anyway, there are interesting implications in both parts I want to comment on. | |||
<br/><br/> | |||
'''''a) making bacteria swim in a certain direction'''''<br/> | |||
It is pretty well known in literature, that bacteria have certain so-called chemotaxis receptors [http://2008.igem.org/Team:Heidelberg/Project/Sensing] on their surface. These receptors are, in nature, used for recognizing attractand molecules (nutrition, i.e. sugar) or repellents (i.e. toxic molecules). | |||
It is possible to influence (I would not say control, but at least strongly influence) the direction in that bacterial colonies on an agar plate swim by putting repellent and attractand molecules at different points on the plate. To give you one example: If I would put aspartate in the middle of an agar plate with E. coli colonies on it, the E. coli would move in direction of the aspartate. Their are different E. coli strains, that do contain different chemotaxis receptors or even no receptors. Furthermore, there are bacteria that swim fast, slow or bacteria that can't even swim at all. Find a comparisn of swimming and not-swimming bacteria [http://parts.mit.edu/igem07/images/f/f3/SwarmingPic.jpg here]. | |||
In general that could be interesting if you wanted to make bacteria swim toward each other. To give you an impression on what swimming bacteria on a plate would look like, here some examples from my bachelor thesis [[media:Bacheloararbeit_Dominik_Niopek_druck.pdf]]. In the 'center' assays, I just put bacteria on either site of the plate. As you can see, the swim rings of the two bacterial colonies meet in the middle after 24 hours (even faster, ie. 6 or 12 hours, depends on the bacteria). In the 'centerline' assay I spottet immobilized bacteria in one line in the middle, and mobile bacteria again on either site of the line. | |||
Those so called swarm assays or swarm agar plates are really simple to prepare, easy to use. If you used different bacteria expressing color pigments (red, green, black), I am sure you could see how one bacteria would take over the space of the others, mix up with them, kill them etc. | |||
<br/><br/> | |||
'''''b) making bacteria kill other bacteria'''''<br/> | |||
In 2008 we also developed a killing mechanism which worked pretty good. The principle is the following: One bacterial strain was engineered to secrete a certain messenger molecule, called Autoinducer-1. The other bacterial strain was engineered to recognize Autoinducer-1 and thereby activate the production of a bacterial toxin called colicin [http://2008.igem.org/Team:Heidelberg/Project/Killing_II]. This means: If both bacterial strains are nearby each other, the one would start to kill the other. It is no problem to label one bacterial strain in red and the other in green and to visualize how the green bacteria die if they are nearby the red ones under a microscope (figure 17 again on [http://2008.igem.org/Team:Heidelberg/Project/Killing_II this] page). The same should also be possible on swarm agar plates. | |||
<br/> | |||
With swimming bacteria on swarm agar plates, you have many options to play around, as their are so many different bacterial strains (swimming slower, faster, not at all, recognizing substances etc.). Take this just as some general comments to think about. In case their is something in that comments, that interests you in particular, please don't hesitate to shoot me an e-mail (d.niopek@gmx.de) or call me (01577-4054784). As I did my bachelor thesis on this topic (swimming bacteria), I would be very happy to provide you with all necessary information and help. | |||
<br/><br/> | |||
--[[User:Dniopek|Dniopek]] 23:18, 9 June 2010 (UTC) | |||
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====Go with the flow==== | |||
[[File:Flow-game-screenshot-4.jpg]] | |||
I found a very interessting game over the internet. | |||
It's a MFA thesis project from 'thatgamecompany' | |||
and called 'flow'. | |||
The game is about a small organism flowing through a watery atmosphere while consuming other small organisms. | |||
Through consuming you as a player can evolve the abilities and appearance of your organism. | |||
[http://thatgamecompany.com/about/ 'Thatgamecompany'] is a small colloboration | |||
of game designers which working only with experimental games like 'flow'. | |||
Everything is mostly about gaining new experiences and inspiring their players | |||
via special sound and atmosphere....and without words! | |||
--[[User:Wawa|Wawa]] 22:14, 9 June 2010 (UTC) | |||
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====Horror Movie about a Human-Animal Synbio Hybrid==== | |||
There is a movie playing in cinemas in germany at the moment about a synthetically created human-animal monster. | |||
It is rather silly and acutally the name "Splice" is scientifically completely incorrect, but if you like to check it out, I'm sure it's worth a laugh (now that you know more about genetics than the average person) | |||
Here's a wikipedia link [[wikipedia:Splice (film)] | |||
Enjoy! | |||
--[[User:Laura iGem|Laura iGem]] 17:51, 9 June 2010 (UTC) | |||
====BioArts in Austrian Magazine==== | |||
An Austrian magazine for genome research, "Genosphären", is running an issue on BioArts and Synthetic Biology this month [http://www.gen-au.at/artikel.jsp?id=932&base=vermitteln&lang=de]. Since you probably won't get your hands on it, here is a round-up of artists that I could not find on your link-list yet. I am sorry if this is somehow redundant in case I missed blog entries, I tried to search through all of them. | |||
- Jun Takita [http://juntakita.com/eng/home.html] created a model of his brain and planted transgenic moss on it. This moss can glow in the dark due to the Luciferase-Gene. This resembles the complex signals that occur in the brain. | |||
- Gary Schneider, who takes genetic portraits of people (which is admittedly not the most original thing to do) [http://garyschneider.net/Portfolio.cfm?nK=7856] | |||
- Adam Brandejs, who presented his sci-fi product, "Genpets", on a website disguised as a normal webshop and raised some outrage with his anti-allergic perfect pet. [http://www.genpets.com] | |||
- Karsten Panzer, who created a colour-coding for the visiual sensation of genetic information [http://www.perzan.de] | |||
I hope this gives some inspiration! | |||
--[[User:Laura iGem|Laura iGem]] 17:35, 6 June 2010 (UTC) | |||
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====Zeit Artikel==== | |||
Synthetische Biologie -Leben 2.0<br /> | |||
Was passiert, wenn es der Bio-Industrie gelingt, den menschlichen Körper neu zu programmieren | |||
* http://www.zeit.de/2010/23/Schoepfungsphantasien | |||
--[[User:Max|max]] 18:00, 5 June 2010 (UTC) | |||
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====The Procreative Dinner==== | |||
An ephemeral work between art, science and gastronomy. Happening by Prune. Nice way of bringing people in touch with the topic...and another example of a collabortation of art and science. | |||
* http://www.prune-art.com/blog/en/index.php?menu_id=1 | |||
--[[User:Mila|Mila]] 14:20, 3 June 2010 (UTC) | |||
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====Six part Series "Synthetische Biologie" on D-Radio==== | |||
[http://www.dradio.de/dlf/sendungen/forschak/1077533/ Schwerpunkt Synthetische Biologie]<br> | |||
--[[User:Bernd|Bernd]] 09:19, 3 June 2010 (UTC) | |||
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====More Photos==== | |||
I have uploaded some photos which I took during the retreat.<br/> Enjoy [[GMU:Synthetic_Biology/Retreat|it]].!<br/> | |||
--[[User:Sharklu|Sharklu]] 00:36, 2 June 2010 (UTC)Lu Jiayuan | |||
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====Back from the retreat==== | |||
The firs images of our lab experiences in Hedeilberg and our fruitful retreat to Asselheim can be found [[GMU:Synthetic_Biology/Retreat|here]]. Please feel free to add more pictures! | |||
--[[User:Sebastian|sebastian]] 16:57, 1 June 2010 (UTC) | |||
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====Richard Jones' comment on Craig Venters successful insertion of a synthetic genome into a bacteria==== | |||
"One might almost suspect that there is a symbiosis going on here, between those scientists anxious to maximise the significance of their work, and bioethicists in search of an issue to raise their own profile. After all, if a piece of science is worth worrying about, it must be important. It’s not that I don’t think that these developments have potentially important societal and ethical implications – but it seems to me that these would be better considered from a standpoint that was a little more critical." Richard Jones on his [http://www.softmachines.org/wordpress/ Blog]. | |||
--[[User:Sebastian|sebastian]] 16:10, 26 May 2010 (UTC) | |||
====First human 'infected with computer virus'==== | |||
[http://news.bbc.co.uk/2/hi/technology/10158517.stm Article] on BBC News | |||
<br> | |||
--[[User:Sebastian|sebastian]] 15:43, 26 May 2010 (UTC) | |||
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====A New Plant==== | |||
Hello! Everyone! | |||
I have built my project page...<br/> | |||
[[GMU:Synthetic_Biology/a new plant| a new plant]]<br/> | |||
Welcome to do something!<br/>-- | |||
[[User:Sharklu|Sharklu]] 16:51, 24 May 2010 (UTC)<br/> | |||
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====To live, to err, to fall, to triumph, to recreate life out of life – the most pretentious bacterium ever==== | |||
''I'd create an animal that excretes meat, just to give vegetarians pause for thought. Ethically, what's the problem with eating a sausage, if it's been harmlessly pooed out by an animal? To sweeten the pill yet further, what if you put pleasure receptors in the animal's colon, so it actively enjoys the sausage-creation process – enjoys it to such a degree that it chases you down the street, yelping in orgasmic delight and producing a string of pan-ready chipolatas? If you think that's disgusting, I'd just like to point out that it's far less revolting than killing a pig with a bolt gun then mashing it up into sausagemeat.'' [http://www.guardian.co.uk/commentisfree/2010/may/24/charlie-brooker-artificial-life-here Charlie Brooker: So, artificial life is here, courtesy of Craig Venter. Time to remix humankind…] | |||
--[[User:Bernd|Bernd]] 11:43, 24 May 2010 (UTC) | |||
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====Some more links on synthetic life==== | |||
[http://www.newscientist.com/article/dn18942-immaculate-creation-birth-of-the-first-synthetic-cell.html Newscienist: Immaculate creation: birth of the first synthetic cell] | |||
[http://www.nytimes.com/2010/05/21/science/21cell.html?ref=science NYTimes: Researchers Say They Created a ‘Synthetic Cell’] | |||
--[[User:Bernd|Bernd]] 09:17, 24 May 2010 (UTC) | |||
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===='''<span style="color:#2F4F4F">Kokoromo : My project is online==== | |||
So I also put up my project... | |||
[[GMU:Synthetic_Biology/ko_ko_ro_mo| ko_ko_ro_mo]] | |||
Please don't be shy and have a look. | |||
I really look forward to discuss it with you all. | |||
--[[User:Wawa|Wawa]] 23:18, 22 May 2010 (UTC) | |||
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====Response to 'My Flower'==== | |||
First response is written ^^ | |||
Have fun! | |||
--[[User:Wawa|Wawa]] 15:51, 22 May 2010 (UTC) | |||
====Update on my page==== | |||
Hello everybody.<br/> | |||
There is new content on my project page.<br/> | |||
It's about my ideas of improving my project.<br/> | |||
The link is below:<br/> | |||
*[[GMU:Synthetic_Biology/My Flower| My Flower]] | |||
Please visit and leave comment!<br/> | |||
Thanks! | |||
--[[User:yuxiaorui|Yu Xiaorui]] 12:02, 22 May 2010 (UTC) | |||
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====Pass the impossimpleble :)==== | |||
Oh my! Are they already this far in development? | |||
I found a pretty amazing TV documentation-series, | |||
(if you can call like that...because its more a idealistic utopia), | |||
of the berlin TVchannel Phoenix. | |||
It is about the possibilities which may occur while living in future with new technologies. It think it would be very interessting for some of you. | |||
To my shame it is only in german at the moment, | |||
but under the link you can find some informations to the technolgies and the scientists. | |||
[http://www.youtube.com/watch?v=NoVS_HvgFfw&feature=PlayList&p=C62483CC011D4E91&playnext_from=PL&playnext=1&index=18] Here comes part 1 of 3 | |||
First Episode - Living in the future - Humans | |||
* houses and also clothes will be connected to the internet to control our health und living status every single moment electronic fibre by Dr. Prof. Sundaresan Jayaraman (Georgie Institute of Technology) | |||
* cars will fly in the air with a satelite electronical guide system to provied us from traffic jams and accidents flying car by Dr. Paul Moller (Moller International) | |||
* stemcells can be used to create new organs tissue engineering by Dr. Stefan Jockenhövel (Helmholz-Institute for biomedical technique) | |||
* 3D genomic printer to create organs layer by layer by Dr. Prof. Thomas Boland (Clemson University) | |||
* food wont make us fat anymore because of genetic engineered proteins by Dr. Prof. Med. Rob Hammer (Wageningen Centre of Food Science) | |||
* cure paraplegia or other neural-muscular deseases with electronic sensor body-implants you can control with your thoughts sensors by Prof. Dr. John Donoghue (Brown University) | |||
* computer surgery sytems controlled by doctors for precise working and without viral infections by Dr. Oliver Burgert (innovation-centre for computer-assisted surgery) | |||
But all that glitters is not gold? Or? | |||
Here also a small outlook what may happend with our health system in future. | |||
Also german *yeah I know I know thats stupid*. | |||
[http://www.ardmediathek.de/ard/servlet/content/3517136?documentId=3961048] | |||
It is called: 'Leichen im Keller' or like the englisch proverb 'scelletons in the (closet) cellar' | |||
I think it is rather nice^^ | |||
I look foward to have some smalltalk about the chances and risks of synbio with you all. | |||
--[[User:Wawa|Wawa]] 18:29, 21 May 2010 (UTC) | |||
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====Its done==== | |||
How does it feel to have created artificial life, Dr Venter? | |||
http://www.independent.co.uk/news/people/profiles/dr-craig-venter-so-doctor-how-does-it-feel-to-have-created-artificial-life-1978873.html | |||
http://www.culturalfarming.com/Resources/civic_media/PostHuman.mov | |||
--[[User:Mila|Mila]] 07:53, 21 May 2010 (UTC) | |||
Craig Venter and his team have built the genome of a bacterium from scratch and incorporated it into a cell to make what they call the world's first synthetic life form | |||
[http://www.guardian.co.uk/science/2010/may/20/craig-venter-synthetic-life-form article]@Guardian.co.uk. Watch the video. | |||
--[[User:Bernd|Bernd]] 11:03, 21 May 2010 (UTC) | |||
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====Links to my project==== | ====Links to my project==== | ||
Hello everbody! | Hello everbody! | ||
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You can Find it in the main page of Synthetic Biology Wiki | You can Find it in the main page of Synthetic Biology Wiki | ||
Or Click here: | Or Click here: | ||
* '''[[GMU:Synthetic_Biology/My Flower| My Flower]]''' | * '''[[GMU:Synthetic_Biology/My Flower| My Flower]]'''<br>I put my review about the presentation I made today on.<br> | ||
I put my review about the presentation I made today on. | |||
'''<span style="color:#FF69B4">Please go and leave comment or suggestion! | '''<span style="color:#FF69B4">Please go and leave comment or suggestion! | ||
That's very important to me!</span>''' | |||
<br>BTW, thank the comment left by Dominic,very helpful!<br> | |||
That's very important to me! | |||
BTW, thank the comment left by Dominic,very helpful! | |||
--[[User:yuxiaorui|Yu Xiaorui]] 17:02, 20 May 2010 (UTC) | --[[User:yuxiaorui|Yu Xiaorui]] 17:02, 20 May 2010 (UTC) | ||
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b) The movie GATTACA might also be interesting [ | b) The movie GATTACA might also be interesting [[wikipedia:Gattaca]] | ||
Furthermore, I already told you about sequencing from simple blood samples. | Furthermore, I already told you about sequencing from simple blood samples. | ||
Sequencing is the technology used to read the genetic code (AGCTTACCTTACC...). Therefor physical DNA (or RNA, I come to that later) is needed. DNA can simply be taken out from cells, i.e. cells of your skin or even blood plasm and serum. You can find some Information about DNA Sequencing on [ | Sequencing is the technology used to read the genetic code (AGCTTACCTTACC...). Therefor physical DNA (or RNA, I come to that later) is needed. DNA can simply be taken out from cells, i.e. cells of your skin or even blood plasm and serum. You can find some Information about DNA Sequencing on [[wikipedia:Sequencing]]. | ||
So why is that interesting? | So why is that interesting? | ||
Line 75: | Line 445: | ||
Coming back to the point: Sequencing RNA from human blood is possible since some years. In the future, as automated sequencing gets better and cheaper, that could give us the oppotunity to have a sort of online-look onto our gene expression. We would simply take blood samples and put them into a full-automatic (pocket?) sequencer. | Coming back to the point: Sequencing RNA from human blood is possible since some years. In the future, as automated sequencing gets better and cheaper, that could give us the oppotunity to have a sort of online-look onto our gene expression. We would simply take blood samples and put them into a full-automatic (pocket?) sequencer. | ||
Today, RNA analysis from blood samples is used i.e. for the [ | Today, RNA analysis from blood samples is used i.e. for the [[wikipedia:HIV test| HIV-diagnosis]] and is also taken into account for [[wikipedia:HIV test|cancer diagnosis]]. In general, if the RNA sequencing from blood will get better and better, we will probably be able to look at our gene expression profile online! | ||
Despite those technologies, another important marker in the blood, especially for the detection of the mood and feelings of the persons are [ | Despite those technologies, another important marker in the blood, especially for the detection of the mood and feelings of the persons are [[wikipedia:Hormones|hormones]]. Hormones have been shown to have a strong influence on many body functions, including blood pressure and heartbeat. Furthermore they have a strong influence on the way we feel and act. Lovers have a certain hormone-cocktail in their blood, people being excited or agressive have a high adrenaline level in their blood. In animal studies it was shown, that by injecting a certain hormone into animals normally not living in groups, they would be nice and friendly living with the group of their kind afterwards (I will look up which animal that was and add that later). | ||
I hope their has been at least some interesting information in this much too long paragraph :) | I hope their has been at least some interesting information in this much too long paragraph :) | ||
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====FYI: Literaturliste Grafik und Gestaltung==== | ====FYI: Literaturliste Grafik und Gestaltung==== | ||
[[GMU:Die neue U-Bahn#Literatur|Literaturliste Grafik und Gestaltung]] | |||
--[[User:Sebastian|sebastian]] 13:11, 6 May 2010 (UTC) | --[[User:Sebastian|sebastian]] 13:11, 6 May 2010 (UTC) | ||
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====Michiko Nitta: Extreme Green Guerrillias==== | ====Michiko Nitta: Extreme Green Guerrillias==== | ||
I think we have mentioned the project already, but give it a look. | I think we have mentioned the project already, but give it a look. | ||
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====Research/Link: Biopunk Manifesto==== | ====Research/Link: Biopunk Manifesto==== | ||
[http://www.ekac.org/biopunk.html The Biopunk Manifesto by Annalee Newitz] | |||
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====Kac goes Hopfengärtner==== | ====Kac goes Hopfengärtner==== | ||
Apparently bioart allstar E.Kac features in his recent work methods employed by B.Hopfengärtner a couple of years ago ;) | Apparently bioart allstar E.Kac features in his recent work methods employed by B.Hopfengärtner a couple of years ago ;) |